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Targeted disruption of EBNA1 in EBV-infected cells attenuated cell growth

Epstein Barr virus (EBV)-encoded nuclear antigen-1 (EBNA1) plays a pivotal in an EBV episome replication and persistence. Despite considerable attempts, there are no EBV drugs or vaccines. We attempted to eradicate EBV episomes by targeting EBNA1 using the transcription activator-like effector nucle...

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Detalles Bibliográficos
Autores principales:	Noh, Ka-Won, Park, Jihyun, Kang, Myung-Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2016
Materias:	Research-Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915242/ https://www.ncbi.nlm.nih.gov/pubmed/26879316 http://dx.doi.org/10.5483/BMBRep.2016.49.4.260

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