Cargando…

An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology

Mostrar otras versiones (1)

Detalles Bibliográficos
Autores principales:	Gingell, Joseph J, Simms, John, Barwell, James, Poyner, David R, Watkins, Harriet A, Pioszak, Augen A, Sexton, Patrick M, Hay, Debbie L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Erratum
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915271/ https://www.ncbi.nlm.nih.gov/pubmed/27463403 http://dx.doi.org/10.1038/celldisc.2016.20

Ejemplares similares

An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology
por: J Gingell, Joseph, et al.
Publicado: (2016)

Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor
por: Booe, Jason M., et al.
Publicado: (2015)

Receptor Activity-modifying Proteins 2 and 3 Generate Adrenomedullin Receptor Subtypes with Distinct Molecular Properties
por: Watkins, Harriet A., et al.
Publicado: (2016)

Receptor activity-modifying protein-dependent effects of mutations in the calcitonin receptor-like receptor: implications for adrenomedullin and calcitonin gene-related peptide pharmacology
por: Watkins, H A, et al.
Publicado: (2014)

Functional Consequences of GPCR Heterodimerization: GPCRs as Allosteric Modulators
por: Haack, Karla K.V., et al.
Publicado: (2011)

Erratum: Distinct loops in arrestin differentially regulate ligand binding within the GPCR opsin
por: Sommer, Martha E., et al.
Publicado: (2012)

Ligand-induced conformational changes in a SMALP-encapsulated GPCR.
por: Routledge, Sarah J., et al.
Publicado: (2020)

The role of ECL2 in CGRP receptor activation: a combined modelling and experimental approach
por: Woolley, Michael. J., et al.
Publicado: (2013)

Allosteric Modulator Leads Hiding in Plain Site: Developing Peptide and Peptidomimetics as GPCR Allosteric Modulators
por: Olson, Keith M., et al.
Publicado: (2021)

Allosteric interactions in the parathyroid hormone GPCR–arrestin complex formation
por: Clark, Lisa J., et al.
Publicado: (2020)

In Silico Study of Allosteric Communication Networks in GPCR Signaling Bias
por: Morales-Pastor, Adrian, et al.
Publicado: (2022)

GPCR oligomers in pharmacology and signaling
por: González-Maeso, Javier
Publicado: (2011)

Crystal Structure of the PAC1R Extracellular Domain Unifies a Consensus Fold for Hormone Recognition by Class B G-Protein Coupled Receptors
por: Kumar, Shiva, et al.
Publicado: (2011)

Allosteric Nanobodies Reveal the Dynamic Range and Diverse Mechanisms of GPCR Activation
por: Staus, Dean P, et al.
Publicado: (2016)

Subcellular location defines GPCR signal transduction
por: Radoux-Mergault, Arthur, et al.
Publicado: (2023)

Receptor activity-modifying protein dependent and independent activation mechanisms in the coupling of calcitonin gene-related peptide and adrenomedullin receptors to Gs
por: Woolley, Michael J., et al.
Publicado: (2017)

Allosteric communication between protomers of dopamine Class A GPCR dimers modulates activation
por: Han, Yang, et al.
Publicado: (2009)

Investigation of GPCR allosterism and dimerization in single living cells using fluorescent ligands
por: Hill, Stehen
Publicado: (2015)

Allosteric activation of proto-oncogene kinase Src by GPCR–beta-arrestin complexes
por: Pakharukova, Natalia, et al.
Publicado: (2021)

Adrenomedullin 2/intermedin is a slow off-rate, long-acting endogenous agonist of the adrenomedullin(2) G protein-coupled receptor
por: Babin, Katie M., et al.
Publicado: (2023)

Adrenomedullin 2/intermedin is a slow off-rate, long-acting endogenous agonist of the adrenomedullin(2) G protein–coupled receptor
por: Babin, Katie M., et al.
Publicado: (2023)

Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody
por: Baidya, Mithu, et al.
Publicado: (2022)

Therapeutic Effects of Modified Gengnianchun Formula on Stress-Induced Diminished Ovarian Reserve Based on Experimental Approaches and Network Pharmacology [Erratum]
Publicado: (2021)

Integrated Multi-Class Classification and Prediction of GPCR Allosteric Modulators by Machine Learning Intelligence
por: Hou, Tianling, et al.
Publicado: (2021)

Structure–activity relationships of the N-terminus of calcitonin gene-related peptide: key roles of alanine-5 and threonine-6 in receptor activation
por: Hay, Debbie L, et al.
Publicado: (2014)

Erratum to study on the mechanism of the Modified Ginseng-Schisandra Decoction (MGSD) in the treatment of recurrent respiratory tract infection (RRTI) based on network pharmacology
Publicado: (2021)

Receptor component protein, an endogenous allosteric modulator of family B G protein coupled receptors
por: Routledge, Sarah J., et al.
Publicado: (2020)

Extracellular loops 1 and 3 and their associated transmembrane regions of the calcitonin receptor-like receptor are needed for CGRP receptor function
por: Barwell, James, et al.
Publicado: (2011)

A Common Molecular Motif Characterizes Extracellular Allosteric Enhancers of GPCR Aminergic Receptors and Suggests Enhancer Mechanism of Action
por: Bernstein, Robert Root, et al.
Publicado: (2014)

Allosteric modulators enhance agonist efficacy by increasing the residence time of a GPCR in the active state
por: Cao, Anne-Marinette, et al.
Publicado: (2021)

Allosteric ligands control the activation of a class C GPCR heterodimer by acting at the transmembrane interface
por: Liu, Lei, et al.
Publicado: (2021)

The GPCR–β-arrestin complex allosterically activates C-Raf by binding its amino terminus
por: Zang, Yunxiang, et al.
Publicado: (2021)

Erratum to: Pharmacology of anticoagulants used in the treatment of venous thromboembolism
por: Nutescu, Edith A., et al.
Publicado: (2016)

Similarity between class A and class B G-protein-coupled receptors exemplified through calcitonin gene-related peptide receptor modelling and mutagenesis studies
por: Vohra, Shabana, et al.
Publicado: (2013)

Erratum: Embryonic transcription is controlled by maternally defined chromatin state
por: Hontelez, Saartje, et al.
Publicado: (2016)

Asymptomatic Erythematous and Tan, Shiny, Well-Defined Plaques: Erratum
Publicado: (2022)

Structural Characterization of Receptor–Receptor Interactions in the Allosteric Modulation of G Protein-Coupled Receptor (GPCR) Dimers
por: Lazim, Raudah, et al.
Publicado: (2021)

BRET biosensors to study GPCR biology, pharmacology, and signal transduction
por: Salahpour, Ali, et al.
Publicado: (2012)

Erratum to: Pathway reporter genes define molecular phenotypes of human cells
por: Zhang, Jitao David, et al.
Publicado: (2017)

Mapping interaction sites within the N-terminus of the calcitonin gene-related peptide receptor; the role of residues 23–60 of the calcitonin receptor-like receptor
por: Barwell, James, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_iqsseqq7rpochqetnsiimmi4iv