A rare balanced nonrobertsonian translocation involving acrocentric chromosomes: Chromosome abnormality of t(13;15)(p11.2;q22.1)

BACKGROUND: Balanced non-robertsonian translocation (RT), involving acrocentric chromosomes, is a rare event and only a few cases are reported. Most of the RTs are balanced involving acrocentric chromosomes with the breakpoints (q10;q10). MATERIALS AND METHODS: Chromosome analysis was performed as p...

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Autores principales: Rupa, Dalvi, Neeraja, Koppaka, Deepak, Chavan, Swarna, Mandava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915285/
https://www.ncbi.nlm.nih.gov/pubmed/27382241
http://dx.doi.org/10.4103/0974-1208.183505
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author Rupa, Dalvi
Neeraja, Koppaka
Deepak, Chavan
Swarna, Mandava
author_facet Rupa, Dalvi
Neeraja, Koppaka
Deepak, Chavan
Swarna, Mandava
author_sort Rupa, Dalvi
collection PubMed
description BACKGROUND: Balanced non-robertsonian translocation (RT), involving acrocentric chromosomes, is a rare event and only a few cases are reported. Most of the RTs are balanced involving acrocentric chromosomes with the breakpoints (q10;q10). MATERIALS AND METHODS: Chromosome analysis was performed as per standard procedure – Giemsa-trypsin banding with 500 band resolution was analyzed for chromosome identification. RESULTS: In the present study, we report a rare balanced non-RTs involving chromosomes 13 and 15 with cytogenetic finding of 46, XX, t(13;15) (p11.2;q22.1). CONCLUSION: To the best of our knowledge, this is the first such report of an unusual non-RT of t(13:15) with (p11.2;q22.1) break points.
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spelling pubmed-49152852016-07-05 A rare balanced nonrobertsonian translocation involving acrocentric chromosomes: Chromosome abnormality of t(13;15)(p11.2;q22.1) Rupa, Dalvi Neeraja, Koppaka Deepak, Chavan Swarna, Mandava J Hum Reprod Sci Case Report BACKGROUND: Balanced non-robertsonian translocation (RT), involving acrocentric chromosomes, is a rare event and only a few cases are reported. Most of the RTs are balanced involving acrocentric chromosomes with the breakpoints (q10;q10). MATERIALS AND METHODS: Chromosome analysis was performed as per standard procedure – Giemsa-trypsin banding with 500 band resolution was analyzed for chromosome identification. RESULTS: In the present study, we report a rare balanced non-RTs involving chromosomes 13 and 15 with cytogenetic finding of 46, XX, t(13;15) (p11.2;q22.1). CONCLUSION: To the best of our knowledge, this is the first such report of an unusual non-RT of t(13:15) with (p11.2;q22.1) break points. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4915285/ /pubmed/27382241 http://dx.doi.org/10.4103/0974-1208.183505 Text en Copyright: © Journal of Human Reproductive Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Rupa, Dalvi
Neeraja, Koppaka
Deepak, Chavan
Swarna, Mandava
A rare balanced nonrobertsonian translocation involving acrocentric chromosomes: Chromosome abnormality of t(13;15)(p11.2;q22.1)
title A rare balanced nonrobertsonian translocation involving acrocentric chromosomes: Chromosome abnormality of t(13;15)(p11.2;q22.1)
title_full A rare balanced nonrobertsonian translocation involving acrocentric chromosomes: Chromosome abnormality of t(13;15)(p11.2;q22.1)
title_fullStr A rare balanced nonrobertsonian translocation involving acrocentric chromosomes: Chromosome abnormality of t(13;15)(p11.2;q22.1)
title_full_unstemmed A rare balanced nonrobertsonian translocation involving acrocentric chromosomes: Chromosome abnormality of t(13;15)(p11.2;q22.1)
title_short A rare balanced nonrobertsonian translocation involving acrocentric chromosomes: Chromosome abnormality of t(13;15)(p11.2;q22.1)
title_sort rare balanced nonrobertsonian translocation involving acrocentric chromosomes: chromosome abnormality of t(13;15)(p11.2;q22.1)
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915285/
https://www.ncbi.nlm.nih.gov/pubmed/27382241
http://dx.doi.org/10.4103/0974-1208.183505
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