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Morphological Characteristics of the Vertebrobasilar Arterial System Are Associated with Vertebrobasilar Dolichoectasia
BACKGROUND: Vertebrobasilar dolichoectasia (VBD) is characterized by abnormal dilation, distortion, and extension of the vertebral artery (VA) and basilar artery (BA). This study investigated whether BA and VA morphological characteristics were factors predicting VBD. MATERIAL/METHODS: Individuals a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915323/ https://www.ncbi.nlm.nih.gov/pubmed/27206494 http://dx.doi.org/10.12659/MSM.895714 |
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author | Wu, Xi Li, Yanjun Huang, Qinghai Liu, Jianmin |
author_facet | Wu, Xi Li, Yanjun Huang, Qinghai Liu, Jianmin |
author_sort | Wu, Xi |
collection | PubMed |
description | BACKGROUND: Vertebrobasilar dolichoectasia (VBD) is characterized by abnormal dilation, distortion, and extension of the vertebral artery (VA) and basilar artery (BA). This study investigated whether BA and VA morphological characteristics were factors predicting VBD. MATERIAL/METHODS: Individuals aged ≥18 years undergoing contrast-enhanced magnetic resonance angiography (CE-MRA) of the head/neck were enrolled in 2012 at Changhai Hospital, Shanghai. Data concerning cardiovascular risk factors were recorded. Bilateral VA diameter and lateral displacement, BA diameter and lateral displacement, VA confluence displacement, and dominant VA (DVA) presence/absence were determined from CE-MRA. VBD was diagnosed using established criteria. DVA and no-DVA groups were compared. Logistic regression analysis was used to identify variables independently associated with VBD. RESULTS: Our study included 1153 individuals, of which 614 (53.3%) had DVA. The DVA group had higher mean age, hypertension prevalence (44.6% vs. 37.5%), and VBD prevalence (8.1% vs. 4.5%), and lower smoking prevalence (24.3% vs. 30.6%), than no-DVA patients. Univariate analysis revealed that age, female sex, hypertension, hyperlipidemia, smoking, alcohol consumption, and DVA presence were associated with VBD occurrence. Multivariate analysis showed that age and presence of a DVA were independently associated with VBD. CONCLUSIONS: Age and presence of DVA are independently associated with VBD. |
format | Online Article Text |
id | pubmed-4915323 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | International Scientific Literature, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-49153232016-06-28 Morphological Characteristics of the Vertebrobasilar Arterial System Are Associated with Vertebrobasilar Dolichoectasia Wu, Xi Li, Yanjun Huang, Qinghai Liu, Jianmin Med Sci Monit Clinical Research BACKGROUND: Vertebrobasilar dolichoectasia (VBD) is characterized by abnormal dilation, distortion, and extension of the vertebral artery (VA) and basilar artery (BA). This study investigated whether BA and VA morphological characteristics were factors predicting VBD. MATERIAL/METHODS: Individuals aged ≥18 years undergoing contrast-enhanced magnetic resonance angiography (CE-MRA) of the head/neck were enrolled in 2012 at Changhai Hospital, Shanghai. Data concerning cardiovascular risk factors were recorded. Bilateral VA diameter and lateral displacement, BA diameter and lateral displacement, VA confluence displacement, and dominant VA (DVA) presence/absence were determined from CE-MRA. VBD was diagnosed using established criteria. DVA and no-DVA groups were compared. Logistic regression analysis was used to identify variables independently associated with VBD. RESULTS: Our study included 1153 individuals, of which 614 (53.3%) had DVA. The DVA group had higher mean age, hypertension prevalence (44.6% vs. 37.5%), and VBD prevalence (8.1% vs. 4.5%), and lower smoking prevalence (24.3% vs. 30.6%), than no-DVA patients. Univariate analysis revealed that age, female sex, hypertension, hyperlipidemia, smoking, alcohol consumption, and DVA presence were associated with VBD occurrence. Multivariate analysis showed that age and presence of a DVA were independently associated with VBD. CONCLUSIONS: Age and presence of DVA are independently associated with VBD. International Scientific Literature, Inc. 2016-05-21 /pmc/articles/PMC4915323/ /pubmed/27206494 http://dx.doi.org/10.12659/MSM.895714 Text en © Med Sci Monit, 2016 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) |
spellingShingle | Clinical Research Wu, Xi Li, Yanjun Huang, Qinghai Liu, Jianmin Morphological Characteristics of the Vertebrobasilar Arterial System Are Associated with Vertebrobasilar Dolichoectasia |
title | Morphological Characteristics of the Vertebrobasilar Arterial System Are Associated with Vertebrobasilar Dolichoectasia |
title_full | Morphological Characteristics of the Vertebrobasilar Arterial System Are Associated with Vertebrobasilar Dolichoectasia |
title_fullStr | Morphological Characteristics of the Vertebrobasilar Arterial System Are Associated with Vertebrobasilar Dolichoectasia |
title_full_unstemmed | Morphological Characteristics of the Vertebrobasilar Arterial System Are Associated with Vertebrobasilar Dolichoectasia |
title_short | Morphological Characteristics of the Vertebrobasilar Arterial System Are Associated with Vertebrobasilar Dolichoectasia |
title_sort | morphological characteristics of the vertebrobasilar arterial system are associated with vertebrobasilar dolichoectasia |
topic | Clinical Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915323/ https://www.ncbi.nlm.nih.gov/pubmed/27206494 http://dx.doi.org/10.12659/MSM.895714 |
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