Positive Selection on a Regulatory Insertion–Deletion Polymorphism in FADS2 Influences Apparent Endogenous Synthesis of Arachidonic Acid

Long chain polyunsaturated fatty acids (LCPUFA) are bioactive components of membrane phospholipids and serve as substrates for signaling molecules. LCPUFA can be obtained directly from animal foods or synthesized endogenously from 18 carbon precursors via the FADS2 coded enzyme. Vegans rely almost e...

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Detalles Bibliográficos
Autores principales: Kothapalli, Kumar S. D., Ye, , Kaixiong, Gadgil, Maithili S., Carlson, Susan E., O’Brien, Kimberly O., Zhang, Ji Yao, Park, Hui Gyu, Ojukwu, Kinsley, Zou, James, Hyon, Stephanie S., Joshi, Kalpana S., Gu, Zhenglong, Keinan, Alon, Brenna, J.Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915354/
https://www.ncbi.nlm.nih.gov/pubmed/27188529
http://dx.doi.org/10.1093/molbev/msw049

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