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Improved Performance of Dynamic Measures of Insulin Response Over Surrogate Indices to Identify Genetic Contributors of Type 2 Diabetes: The GUARDIAN Consortium

Type 2 diabetes (T2D) is a heterogeneous disorder with contributions from peripheral insulin resistance and β-cell dysfunction. For minimization of phenotypic heterogeneity, quantitative intermediate phenotypes characterizing basal glucose homeostasis (insulin resistance and HOMA of insulin resistan...

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Detalles Bibliográficos
Autores principales:	Palmer, Nicholette D., Wagenknecht, Lynne E., Langefeld, Carl D., Wang, Nan, Buchanan, Thomas A., Xiang, Anny H., Allayee, Hooman, Bergman, Richard N., Raffel, Leslie J., Chen, Yii-Der Ida, Haritunians, Talin, Fingerlin, Tasha, Goodarzi, Mark O., Taylor, Kent D., Rotter, Jerome I., Watanabe, Richard M., Bowden, Donald W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2016
Materias:	Genetics/Genomes/Proteomics/Metabolomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915581/ https://www.ncbi.nlm.nih.gov/pubmed/27207554 http://dx.doi.org/10.2337/db15-1543

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