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Dissociation Dynamics of XPC-RAD23B from Damaged DNA Is a Determining Factor of NER Efficiency

XPC-RAD23B (XPC) plays a critical role in human nucleotide excision repair (hNER) as this complex recognizes DNA adducts to initiate NER. To determine the mutagenic potential of structurally different bulky DNA damages, various studies have been conducted to define the correlation of XPC-DNA damage...

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Detalles Bibliográficos
Autores principales:	Hilton, Benjamin, Gopal, Sathyaraj, Xu, Lifang, Mazumder, Sharmistha, Musich, Phillip R., Cho, Bongsup P., Zou, Yue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915676/ https://www.ncbi.nlm.nih.gov/pubmed/27327897 http://dx.doi.org/10.1371/journal.pone.0157784

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