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Human Adenovirus Serotype 3 Vector Packaged by a Rare Serotype 14 Hexon
Recombinant adenovirus serotype 3 (rAd3), which infects cells through the receptor desmoglein 2 (DSG2), has been investigated as a vector for gene therapy or vaccination. However, pre-existing anti-vector immunity may limit the practical application of rAd3. In this study, we investigated the seropr...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915686/ https://www.ncbi.nlm.nih.gov/pubmed/27328032 http://dx.doi.org/10.1371/journal.pone.0156984 |