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A Mechanistic Beta-Binomial Probability Model for mRNA Sequencing Data
A main application for mRNA sequencing (mRNAseq) is determining lists of differentially-expressed genes (DEGs) between two or more conditions. Several software packages exist to produce DEGs from mRNAseq data, but they typically yield different DEGs, sometimes markedly so. The underlying probability...
Autores principales: | Smith, Gregory R., Birtwistle, Marc R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915702/ https://www.ncbi.nlm.nih.gov/pubmed/27326762 http://dx.doi.org/10.1371/journal.pone.0157828 |
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