E-Flux2 and SPOT: Validated Methods for Inferring Intracellular Metabolic Flux Distributions from Transcriptomic Data

BACKGROUND: Several methods have been developed to predict system-wide and condition-specific intracellular metabolic fluxes by integrating transcriptomic data with genome-scale metabolic models. While powerful in many settings, existing methods have several shortcomings, and it is unclear which met...

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Detalles Bibliográficos
Autores principales: Kim, Min Kyung, Lane, Anatoliy, Kelley, James J., Lun, Desmond S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915706/
https://www.ncbi.nlm.nih.gov/pubmed/27327084
http://dx.doi.org/10.1371/journal.pone.0157101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915706/
https://www.ncbi.nlm.nih.gov/pubmed/27327084
http://dx.doi.org/10.1371/journal.pone.0157101

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