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Redesigning Aldolase Stereoselectivity by Homologous Grafting

The 2-deoxy-d-ribose-5-phosphate aldolase (DERA) offers access to highly desirable building blocks for organic synthesis by catalyzing a stereoselective C-C bond formation between acetaldehyde and certain electrophilic aldehydes. DERA´s potential is particularly highlighted by the ability to catalyz...

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Detalles Bibliográficos
Autores principales: Bisterfeld, Carolin, Classen, Thomas, Küberl, Irene, Henßen, Birgit, Metz, Alexander, Gohlke, Holger, Pietruszka, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915726/
https://www.ncbi.nlm.nih.gov/pubmed/27327271
http://dx.doi.org/10.1371/journal.pone.0156525

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