Cargando…
Rapid Return of Spontaneous Respiration after General Anesthesia with Sugammadex in a Patient with Myasthenia Gravis
Myasthenia gravis causes weakness and fatigue of the skeletal muscles, including respiratory muscles. When immobile surgical fields are needed, neuromuscular blocking agents (NMBAs) are often administered to block muscle activity, leading to an immobile surgical field and respiratory arrest. Acetylc...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Yonsei University Wonju College of Medicine
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915766/ https://www.ncbi.nlm.nih.gov/pubmed/27358839 http://dx.doi.org/10.15280/jlm.2016.6.1.43 |
_version_ | 1782438734922252288 |
---|---|
author | Kim, Raing Kyu Kim, Soon Yul |
author_facet | Kim, Raing Kyu Kim, Soon Yul |
author_sort | Kim, Raing Kyu |
collection | PubMed |
description | Myasthenia gravis causes weakness and fatigue of the skeletal muscles, including respiratory muscles. When immobile surgical fields are needed, neuromuscular blocking agents (NMBAs) are often administered to block muscle activity, leading to an immobile surgical field and respiratory arrest. Acetylcholinesterase inhibitors are administered to reverse the muscle block, promoting spontaneous respiration for patient recovery. If immobile surgical fields are required in myasthenic patient operations, NMBAs should be administered. However, recovery from NMBAs using acetylcholinesterase inhibitors might be delayed in myasthenic patients due to their intake of medicines that already inhibit cholinesterase, resulting in a delay in spontaneous respiration. Sugammadex is a recently introduced medicine that reverses muscle blocks through a different mechanism from acetylcholinesterase inhibitors and can be administered to facilitate the return of spontaneous respiration in myasthenic patients. Our experience of the rapid return to spontaneous respiration of a myasthenic patient with Sugammadex is reported in this paper. |
format | Online Article Text |
id | pubmed-4915766 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Yonsei University Wonju College of Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-49157662016-06-29 Rapid Return of Spontaneous Respiration after General Anesthesia with Sugammadex in a Patient with Myasthenia Gravis Kim, Raing Kyu Kim, Soon Yul J Lifestyle Med Case Report Myasthenia gravis causes weakness and fatigue of the skeletal muscles, including respiratory muscles. When immobile surgical fields are needed, neuromuscular blocking agents (NMBAs) are often administered to block muscle activity, leading to an immobile surgical field and respiratory arrest. Acetylcholinesterase inhibitors are administered to reverse the muscle block, promoting spontaneous respiration for patient recovery. If immobile surgical fields are required in myasthenic patient operations, NMBAs should be administered. However, recovery from NMBAs using acetylcholinesterase inhibitors might be delayed in myasthenic patients due to their intake of medicines that already inhibit cholinesterase, resulting in a delay in spontaneous respiration. Sugammadex is a recently introduced medicine that reverses muscle blocks through a different mechanism from acetylcholinesterase inhibitors and can be administered to facilitate the return of spontaneous respiration in myasthenic patients. Our experience of the rapid return to spontaneous respiration of a myasthenic patient with Sugammadex is reported in this paper. Yonsei University Wonju College of Medicine 2016-03 2016-03-31 /pmc/articles/PMC4915766/ /pubmed/27358839 http://dx.doi.org/10.15280/jlm.2016.6.1.43 Text en © 2016 Journal of Lifestyle Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Kim, Raing Kyu Kim, Soon Yul Rapid Return of Spontaneous Respiration after General Anesthesia with Sugammadex in a Patient with Myasthenia Gravis |
title | Rapid Return of Spontaneous Respiration after General Anesthesia with Sugammadex in a Patient with Myasthenia Gravis |
title_full | Rapid Return of Spontaneous Respiration after General Anesthesia with Sugammadex in a Patient with Myasthenia Gravis |
title_fullStr | Rapid Return of Spontaneous Respiration after General Anesthesia with Sugammadex in a Patient with Myasthenia Gravis |
title_full_unstemmed | Rapid Return of Spontaneous Respiration after General Anesthesia with Sugammadex in a Patient with Myasthenia Gravis |
title_short | Rapid Return of Spontaneous Respiration after General Anesthesia with Sugammadex in a Patient with Myasthenia Gravis |
title_sort | rapid return of spontaneous respiration after general anesthesia with sugammadex in a patient with myasthenia gravis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915766/ https://www.ncbi.nlm.nih.gov/pubmed/27358839 http://dx.doi.org/10.15280/jlm.2016.6.1.43 |
work_keys_str_mv | AT kimraingkyu rapidreturnofspontaneousrespirationaftergeneralanesthesiawithsugammadexinapatientwithmyastheniagravis AT kimsoonyul rapidreturnofspontaneousrespirationaftergeneralanesthesiawithsugammadexinapatientwithmyastheniagravis |