Cargando…
Nuclear proton dynamics and interactions with calcium signaling
Biochemical signals acting on the nucleus can regulate gene expression. Despite the inherent affinity of nucleic acids and nuclear proteins (e.g. transcription factors) for protons, little is known about the mechanisms that regulate nuclear pH (pH(nuc)), and how these could be exploited to control g...
Autores principales: | Hulikova, Alzbeta, Swietach, Pawel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915819/ https://www.ncbi.nlm.nih.gov/pubmed/26183898 http://dx.doi.org/10.1016/j.yjmcc.2015.07.003 |
Ejemplares similares
-
Dual Role of CO(2)/HCO(3)(−) Buffer in the Regulation of Intracellular pH of Three-dimensional Tumor Growths
por: Hulikova, Alzbeta, et al.
Publicado: (2011) -
Importance of Intracellular pH in Determining the Uptake and Efficacy of the Weakly Basic Chemotherapeutic Drug, Doxorubicin
por: Swietach, Pawel, et al.
Publicado: (2012) -
Single-cell O(2) exchange imaging shows that cytoplasmic diffusion is a dominant barrier to efficient gas transport in red blood cells
por: Richardson, Sarah L., et al.
Publicado: (2020) -
Solute exchange through gap junctions lessens the adverse effects of inactivating mutations in metabolite-handling genes
por: Monterisi, Stefania, et al.
Publicado: (2022) -
Carbonic anhydrase IX is a pH-stat that sets an acidic tumour extracellular pH in vivo
por: Lee, Shen-Han, et al.
Publicado: (2018)