TBX2 represses PTEN in rhabdomyosarcoma and skeletal muscle

Rhabdomyosarcoma (RMS) is the most frequent soft tissue sarcoma in children that shares many features of developing skeletal muscle. TBX2, a T-box family member, is highly up regulated in tumor cells of both major RMS subtypes where it functions as an oncogene. TBX2 is a repressor that is often over...

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Detalles Bibliográficos
Autores principales: Zhu, Bo, Zhang, Meiling, Williams, Elizabeth M., Keller, Charles, Mansoor, Atiya, Davie, Judith K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916052/
https://www.ncbi.nlm.nih.gov/pubmed/26686089
http://dx.doi.org/10.1038/onc.2015.486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916052/
https://www.ncbi.nlm.nih.gov/pubmed/26686089
http://dx.doi.org/10.1038/onc.2015.486

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