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Arginyltransferase ATE1 suppresses cell tumorigenic potential and inversely correlates with metastases in human cancers

Arginylation is an emerging posttranslational modification mediated by arginyltransferase (ATE1) that is essential for mammalian embryogenesis and regulation of the cytoskeleton. Here, we discovered that Ate1 knockout embryonic fibroblasts exhibit tumorigenic properties, including abnormally rapid c...

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Detalles Bibliográficos
Autores principales:	Rai, Reena, Zhang, Fangliang, Colavita, Kristen, Leu, Nicolae Adrian, Kurosaka, Satoshi, Kumar, Akhilesh, Birnbaum, Michael D., Győrffy, Balázs, Dong, Dawei W., Shtutman, Michael, Kashina, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916053/ https://www.ncbi.nlm.nih.gov/pubmed/26686093 http://dx.doi.org/10.1038/onc.2015.473

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