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Comparison of CRISPR/Cas9 and TALENs on editing an integrated EGFP gene in the genome of HEK293FT cells

BACKGROUND: Genome editors such as CRISPR/Cas9 and TALENs are at the forefront of research into methodologies for targeted modification of the mammalian genome. To date few comparative studies have been carried out to investigate the difference of genome editing characteristics between CRISPR/Cas9 a...

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Detalles Bibliográficos
Autores principales: He, Zuyong, Proudfoot, Chris, Whitelaw, C. Bruce A., Lillico, Simon G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916124/
https://www.ncbi.nlm.nih.gov/pubmed/27390654
http://dx.doi.org/10.1186/s40064-016-2536-3