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Adipocyte-specific CD1d-deficiency mitigates diet-induced obesity and insulin resistance in mice

It has been shown that CD1d expression and glycolipid-reactive, CD1d-restricted NKT cells exacerbate the development of obesity and insulin resistance in mice. However, the relevant CD1d-expressing cells that influence the effects of NKT cells on the progression of obesity remain incompletely define...

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Detalles Bibliográficos
Autores principales: Satoh, Masashi, Hoshino, Miyuki, Fujita, Koki, Iizuka, Misao, Fujii, Satoshi, Clingan, Christopher S., Van Kaer, Luc, Iwabuchi, Kazuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916414/
https://www.ncbi.nlm.nih.gov/pubmed/27329323
http://dx.doi.org/10.1038/srep28473