IL-6 mediates differentiation disorder during spermatogenesis in obesity-associated inflammation by affecting the expression of Zfp637 through the SOCS3/STAT3 pathway

Zfp637 is a recently identified zinc finger protein, and its functions remain largely unknown. Here, we innovatively demonstrate the effects of Zfp637 on the differentiation of mouse spermatogonia and on its downstream target gene SOX2 in vitro. Obesity has been recognized as a chronic inflammatory...

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Detalles Bibliográficos
Autores principales: Huang, Guizhen, Yuan, Miao, Zhang, Jie, Li, Jun, Gong, Di, Li, Yanyan, Lin, Ping, Huang, Lugang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916425/
https://www.ncbi.nlm.nih.gov/pubmed/27329259
http://dx.doi.org/10.1038/srep28012

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