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R-spondin 2 promotes acetylcholine receptor clustering at the neuromuscular junction via Lgr5
At the neuromuscular junction (NMJ), acetylcholine receptor (AChR) clustering is mediated by spinal motor neuron (SMN)-derived agrin and its receptors on the muscle, the low-density lipoprotein receptor-related protein 4 (LRP4) and muscle-specific receptor tyrosine kinase (MuSK). Additionally, AChR...
Autores principales: | Nakashima, Hiroaki, Ohkawara, Bisei, Ishigaki, Shinsuke, Fukudome, Takayasu, Ito, Kenyu, Tsushima, Mikito, Konishi, Hiroyuki, Okuno, Tatsuya, Yoshimura, Toshiro, Ito, Mikako, Masuda, Akio, Sobue, Gen, Kiyama, Hiroshi, Ishiguro, Naoki, Ohno, Kinji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916433/ https://www.ncbi.nlm.nih.gov/pubmed/27328992 http://dx.doi.org/10.1038/srep28512 |
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