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Evaluation of the inhibition potential of plumbagin against cytochrome P450 using LC-MS/MS and cocktail approach

Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone), a natural naphthoquinone compound isolated from roots of Plumbago zeylanica L., has drawn a lot of attention for its plenty of pharmacological properties including antidiabetes and anti-cancer. The aim of this study was to investigate the effects of...

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Detalles Bibliográficos
Autores principales: Chen, Ang, Zhou, Xiaojing, Tang, Shuowen, Liu, Mingyao, Wang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916434/
https://www.ncbi.nlm.nih.gov/pubmed/27329697
http://dx.doi.org/10.1038/srep28482