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Trehalose, sucrose and raffinose are novel activators of autophagy in human keratinocytes through an mTOR-independent pathway

Trehalose is a natural disaccharide that is found in a diverse range of organisms but not in mammals. Autophagy is a process which mediates the sequestration, lysosomal delivery and degradation of proteins and organelles. Studies have shown that trehalose exerts beneficial effects through inducing a...

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Detalles Bibliográficos
Autores principales: Chen, Xu, Li, Min, Li, Li, Xu, Song, Huang, Dan, Ju, Mei, Huang, Ju, Chen, Kun, Gu, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916512/
https://www.ncbi.nlm.nih.gov/pubmed/27328819
http://dx.doi.org/10.1038/srep28423