The spectrum effect in tests for risk prediction, screening, and diagnosis

The spectrum effect describes the variation between settings in performance of tests used to predict, screen for, and diagnose disease. In particular, the predictive use of a test may be different when it is applied in a general population rather than in the study sample in which it was first develo...

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Detalles Bibliográficos
Autores principales: Usher-Smith, Juliet A, Sharp,, Stephen J, Griffin, Simon J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2016
Materias:
Research Methods & Reporting
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916916/
https://www.ncbi.nlm.nih.gov/pubmed/27334281
http://dx.doi.org/10.1136/bmj.i3139
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author Usher-Smith, Juliet A
Sharp,, Stephen J
Griffin, Simon J
author_facet Usher-Smith, Juliet A
Sharp,, Stephen J
Griffin, Simon J
author_sort Usher-Smith, Juliet A
collection PubMed
description The spectrum effect describes the variation between settings in performance of tests used to predict, screen for, and diagnose disease. In particular, the predictive use of a test may be different when it is applied in a general population rather than in the study sample in which it was first developed. This article discusses the impact of the spectrum effect on measures of test performance, and its implications for the development, evaluation, application, and implementation of such tests.
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spelling pubmed-49169162016-06-24 The spectrum effect in tests for risk prediction, screening, and diagnosis Usher-Smith, Juliet A Sharp,, Stephen J Griffin, Simon J BMJ Research Methods & Reporting The spectrum effect describes the variation between settings in performance of tests used to predict, screen for, and diagnose disease. In particular, the predictive use of a test may be different when it is applied in a general population rather than in the study sample in which it was first developed. This article discusses the impact of the spectrum effect on measures of test performance, and its implications for the development, evaluation, application, and implementation of such tests. BMJ Publishing Group Ltd. 2016-06-22 /pmc/articles/PMC4916916/ /pubmed/27334281 http://dx.doi.org/10.1136/bmj.i3139 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 3.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/3.0/.
spellingShingle Research Methods & Reporting
Usher-Smith, Juliet A
Sharp,, Stephen J
Griffin, Simon J
The spectrum effect in tests for risk prediction, screening, and diagnosis
title The spectrum effect in tests for risk prediction, screening, and diagnosis
title_full The spectrum effect in tests for risk prediction, screening, and diagnosis
title_fullStr The spectrum effect in tests for risk prediction, screening, and diagnosis
title_full_unstemmed The spectrum effect in tests for risk prediction, screening, and diagnosis
title_short The spectrum effect in tests for risk prediction, screening, and diagnosis
title_sort spectrum effect in tests for risk prediction, screening, and diagnosis
topic Research Methods & Reporting
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916916/
https://www.ncbi.nlm.nih.gov/pubmed/27334281
http://dx.doi.org/10.1136/bmj.i3139
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