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A New Algorithm to Optimize Maximal Information Coefficient

The maximal information coefficient (MIC) captures dependences between paired variables, including both functional and non-functional relationships. In this paper, we develop a new method, ChiMIC, to calculate the MIC values. The ChiMIC algorithm uses the chi-square test to terminate grid optimizati...

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Detalles Bibliográficos
Autores principales: Chen, Yuan, Zeng, Ying, Luo, Feng, Yuan, Zheming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917098/
https://www.ncbi.nlm.nih.gov/pubmed/27333001
http://dx.doi.org/10.1371/journal.pone.0157567
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author Chen, Yuan
Zeng, Ying
Luo, Feng
Yuan, Zheming
author_facet Chen, Yuan
Zeng, Ying
Luo, Feng
Yuan, Zheming
author_sort Chen, Yuan
collection PubMed
description The maximal information coefficient (MIC) captures dependences between paired variables, including both functional and non-functional relationships. In this paper, we develop a new method, ChiMIC, to calculate the MIC values. The ChiMIC algorithm uses the chi-square test to terminate grid optimization and then removes the restriction of maximal grid size limitation of original ApproxMaxMI algorithm. Computational experiments show that ChiMIC algorithm can maintain same MIC values for noiseless functional relationships, but gives much smaller MIC values for independent variables. For noise functional relationship, the ChiMIC algorithm can reach the optimal partition much faster. Furthermore, the MCN values based on MIC calculated by ChiMIC can capture the complexity of functional relationships in a better way, and the statistical powers of MIC calculated by ChiMIC are higher than those calculated by ApproxMaxMI. Moreover, the computational costs of ChiMIC are much less than those of ApproxMaxMI. We apply the MIC values tofeature selection and obtain better classification accuracy using features selected by the MIC values from ChiMIC.
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spelling pubmed-49170982016-07-08 A New Algorithm to Optimize Maximal Information Coefficient Chen, Yuan Zeng, Ying Luo, Feng Yuan, Zheming PLoS One Research Article The maximal information coefficient (MIC) captures dependences between paired variables, including both functional and non-functional relationships. In this paper, we develop a new method, ChiMIC, to calculate the MIC values. The ChiMIC algorithm uses the chi-square test to terminate grid optimization and then removes the restriction of maximal grid size limitation of original ApproxMaxMI algorithm. Computational experiments show that ChiMIC algorithm can maintain same MIC values for noiseless functional relationships, but gives much smaller MIC values for independent variables. For noise functional relationship, the ChiMIC algorithm can reach the optimal partition much faster. Furthermore, the MCN values based on MIC calculated by ChiMIC can capture the complexity of functional relationships in a better way, and the statistical powers of MIC calculated by ChiMIC are higher than those calculated by ApproxMaxMI. Moreover, the computational costs of ChiMIC are much less than those of ApproxMaxMI. We apply the MIC values tofeature selection and obtain better classification accuracy using features selected by the MIC values from ChiMIC. Public Library of Science 2016-06-22 /pmc/articles/PMC4917098/ /pubmed/27333001 http://dx.doi.org/10.1371/journal.pone.0157567 Text en © 2016 Chen et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Chen, Yuan
Zeng, Ying
Luo, Feng
Yuan, Zheming
A New Algorithm to Optimize Maximal Information Coefficient
title A New Algorithm to Optimize Maximal Information Coefficient
title_full A New Algorithm to Optimize Maximal Information Coefficient
title_fullStr A New Algorithm to Optimize Maximal Information Coefficient
title_full_unstemmed A New Algorithm to Optimize Maximal Information Coefficient
title_short A New Algorithm to Optimize Maximal Information Coefficient
title_sort new algorithm to optimize maximal information coefficient
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917098/
https://www.ncbi.nlm.nih.gov/pubmed/27333001
http://dx.doi.org/10.1371/journal.pone.0157567
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