Cargando…
Recombinant AAV Vectors for Enhanced Expression of Authentic IgG
Adeno-associated virus (AAV) has become a vector of choice for the treatment of a variety of genetic diseases that require safe and long-term delivery of a missing protein. Muscle-directed gene transfer for delivery of protective antibodies against AIDS viruses and other pathogens has been used expe...
Autores principales: | Fuchs, Sebastian P., Martinez-Navio, José M., Gao, Guangping, Desrosiers, Ronald C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917256/ https://www.ncbi.nlm.nih.gov/pubmed/27332822 http://dx.doi.org/10.1371/journal.pone.0158009 |
Ejemplares similares
-
Glycoengineering of AAV-delivered monoclonal antibodies yields increased ADCC activity
por: Termini, James M., et al.
Publicado: (2020) -
Liver-Directed but Not Muscle-Directed AAV-Antibody Gene Transfer Limits Humoral Immune Responses in Rhesus Monkeys
por: Fuchs, Sebastian P., et al.
Publicado: (2019) -
AAV-Delivered Antibody Mediates Significant Protective Effects against SIVmac239 Challenge in the Absence of Neutralizing Activity
por: Fuchs, Sebastian P., et al.
Publicado: (2015) -
Long-Term Delivery of an Anti-SIV Monoclonal Antibody With AAV
por: Martinez-Navio, José M., et al.
Publicado: (2020) -
High concordance of ELISA and neutralization assays allows for the detection of antibodies to individual AAV serotypes
por: Gardner, Matthew R., et al.
Publicado: (2022)