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Impaired dynamic cerebrovascular response to hypercapnia predicts development of white matter hyperintensities

PURPOSE: To evaluate the relationship between both dynamic and steady-state measures of cerebrovascular reactivity (CVR) and the progression of age-related white matter disease. METHODS: Blood oxygen level-dependent (BOLD) MRI CVR scans were acquired from forty-five subjects (age range: 50–90 years,...

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Detalles Bibliográficos
Autores principales:	Sam, Kevin, Conklin, John, Holmes, Kenneth R., Sobczyk, Olivia, Poublanc, Julien, Crawley, Adrian P., Mandell, Daniel M., Venkatraghavan, Lakshmikumar, Duffin, James, Fisher, Joseph A., Black, Sandra E., Mikulis, David J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917393/ https://www.ncbi.nlm.nih.gov/pubmed/27358765 http://dx.doi.org/10.1016/j.nicl.2016.05.008

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