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Induction of Nuclear Enlargement and Senescence by Sirtuin Inhibitors in Glioblastoma Cells
Sirtuin family members with lysine deacetylase activity are known to play an important role in anti-aging and longevity. Cellular senescence is one of the hallmarks of aging, and downregulation of sirtuin is reported to induce premature senescence. In this study, we investigated the effects of small...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Korean Association of Immunologists
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917402/ https://www.ncbi.nlm.nih.gov/pubmed/27340387 http://dx.doi.org/10.4110/in.2016.16.3.183 |