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Development of a prediction system for anti-tuberculosis drug-induced liver injury in Japanese patients

Drug-induced liver injury (DILI) is a common adverse drug reaction in patients receiving antituberculosis (anti-TB) treatment. Among the anti-TB agents, isoniazid (INH) is the primary drug that causes hepatotoxicity in TB patients with DILI. Previous reports in several populations have consistently...

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Detalles Bibliográficos
Autores principales: Mushiroda, Taisei, Yanai, Hideki, Yoshiyama, Takashi, Sasaki, Yuka, Okumura, Masao, Ogata, Hideo, Tokunaga, Katsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917605/
https://www.ncbi.nlm.nih.gov/pubmed/27340556
http://dx.doi.org/10.1038/hgv.2016.14