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Clusterin facilitates apoptotic cell clearance and prevents apoptotic cell-induced autoimmune responses
Clusterin (Clu), an extracellular chaperone, exhibits characteristics of soluble innate immunity receptors, as assessed by its ability to bind some bacteria strains. In this study, we report that Clu also binds specifically to late apoptotic cells but not to live, early apoptotic, or necrotic cells....
Autores principales: | Cunin, P, Beauvillain, C, Miot, C, Augusto, J-F, Preisser, L, Blanchard, S, Pignon, P, Scotet, M, Garo, E, Fremaux, I, Chevailler, A, Subra, J-F, Blanco, P, Wilson, M R, Jeannin, P, Delneste, Y |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917652/ https://www.ncbi.nlm.nih.gov/pubmed/27148688 http://dx.doi.org/10.1038/cddis.2016.113 |
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