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Nrf2-driven TERT regulates pentose phosphate pathway in glioblastoma

Given the involvement of telomerase activation and dysregulated metabolism in glioma progression, the connection between these two critical players was investigated. Pharmacological inhibition of human Telomerase reverse transcriptase (hTERT) by Costunolide induced glioma cell apoptosis in a reactiv...

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Detalles Bibliográficos
Autores principales: Ahmad, F, Dixit, D, Sharma, V, Kumar, A, Joshi, S D, Sarkar, C, Sen, E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917655/
https://www.ncbi.nlm.nih.gov/pubmed/27148686
http://dx.doi.org/10.1038/cddis.2016.117