Chitohexaose protects against acetaminophen-induced hepatotoxicity in mice

Acetaminophen (N-acetyl-para-aminophenol (APAP)) toxicity causes acute liver failure by inducing centrilobular hepatic damage as a consequence of mitochondrial oxidative stress. Sterile inflammation, triggered by hepatic damage, facilitates gut bacterial translocation leading to systemic inflammatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Barman, P K, Mukherjee, R, Prusty, B K, Suklabaidya, S, Senapati, S, Ravindran, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917664/
https://www.ncbi.nlm.nih.gov/pubmed/27171266
http://dx.doi.org/10.1038/cddis.2016.131

Ejemplares similares

Ejemplares similares