Hearts deficient in both Mfn1 and Mfn2 are protected against acute myocardial infarction

Mitochondria alter their shape by undergoing cycles of fusion and fission. Changes in mitochondrial morphology impact on the cellular response to stress, and their interactions with other organelles such as the sarcoplasmic reticulum (SR). Inhibiting mitochondrial fission can protect the heart again...

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Detalles Bibliográficos
Autores principales: Hall, A R, Burke, N, Dongworth, R K, Kalkhoran, S B, Dyson, A, Vicencio, J M, Dorn II, G W, Yellon, D M, Hausenloy, D J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917668/
https://www.ncbi.nlm.nih.gov/pubmed/27228353
http://dx.doi.org/10.1038/cddis.2016.139

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