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Sirtuins and Cancer: Role in the Epithelial-Mesenchymal Transition

The human sirtuins (SIRT1–SIRT7) enzymes are a highly conserved family of NAD(+)-dependent histone deacetylases, which play a critical role in the regulation of a large number of metabolic pathways involved in stress response and aging. Cancer is an age-associated disease, and sirtuins may have a co...

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Detalles Bibliográficos
Autores principales:	Palmirotta, Raffaele, Cives, Mauro, Della-Morte, David, Capuani, Barbara, Lauro, Davide, Guadagni, Fiorella, Silvestris, Franco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917709/ https://www.ncbi.nlm.nih.gov/pubmed/27379175 http://dx.doi.org/10.1155/2016/3031459

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