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Oncogenic Sox2 regulates and cooperates with VRK1 in cell cycle progression and differentiation

Sox2 is a pluripotency transcription factor that as an oncogene can also regulate cell proliferation. Therefore, genes implicated in several different aspects of cell proliferation, such as the VRK1 chromatin-kinase, are candidates to be targets of Sox2. Sox 2 and VRK1 colocalize in nuclei of prolif...

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Detalles Bibliográficos
Autores principales:	Moura, David S., Fernández, Isabel F., Marín-Royo, Gema, López-Sánchez, Inmaculada, Martín-Doncel, Elena, Vega, Francisco M., Lazo, Pedro A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917848/ https://www.ncbi.nlm.nih.gov/pubmed/27334688 http://dx.doi.org/10.1038/srep28532

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