GFI1(36N) as a therapeutic and prognostic marker for myelodysplastic syndrome

Inherited gene variants play an important role in malignant diseases. The transcriptional repressor growth factor independence 1 (GFI1) regulates hematopoietic stem cell (HSC) self-renewal and differentiation. A single-nucleotide polymorphism of GFI1 (rs34631763) generates a protein with an asparagi...

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Detalles Bibliográficos
Autores principales: Botezatu, Lacramioara, Michel, Lars C., Makishima, Hideki, Schroeder, Thomas, Germing, Ulrich, Haas, Rainer, van der Reijden, Bert, Marneth, Anne E., Bergevoet, Saskia M., Jansen, Joop H., Przychodzen, Bartlomiej, Wlodarski, Marcin, Niemeyer, Charlotte, Platzbecker, Uwe, Ehninger, Gerhard, Unnikrishnan, Ashwin, Beck, Dominik, Pimanda, John, Hellström-Lindberg, Eva, Malcovati, Luca, Boultwood, Jacqueline, Pellagatti, Andrea, Papaemmanuil, Elli, Le Coutre, Philipp, Kaeda, Jaspal, Opalka, Bertram, Möröy, Tarik, Dührsen, Ulrich, Maciejewski, Jaroslaw, Khandanpour, Cyrus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Inc 2016
Materias:
Malignant Hematopoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917888/
https://www.ncbi.nlm.nih.gov/pubmed/27080012
http://dx.doi.org/10.1016/j.exphem.2016.04.001

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