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ARCII: A phase II trial of the HIV protease inhibitor Nelfinavir in combination with chemoradiation for locally advanced inoperable pancreatic cancer

BACKGROUND AND PURPOSE: Nelfinavir can enhance intrinsic radiosensitivity, reduce hypoxia and improve vascularity. We conducted a phase II trial combining nelfinavir with chemoradiotherapy (CRT) for locally advanced inoperable pancreatic cancer (LAPC). MATERIALS AND METHODS: Radiotherapy (50.4 Gy/28...

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Detalles Bibliográficos
Autores principales:	Wilson, James M., Fokas, Emmanouil, Dutton, Susan J., Patel, Neel, Hawkins, Maria A., Eccles, Cynthia, Chu, Kwun-Ye, Durrant, Lisa, Abraham, Aswin G., Partridge, Mike, Woodward, Martha, O’Neill, Eric, Maughan, Tim, McKenna, W. Gillies, Mukherjee, Somnath, Brunner, Thomas B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Scientific Publishers 2016
Materias:	Phase II trial
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917892/ https://www.ncbi.nlm.nih.gov/pubmed/27117177 http://dx.doi.org/10.1016/j.radonc.2016.03.021

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