Progerin, the protein responsible for the Hutchinson-Gilford progeria syndrome, increases the unrepaired DNA damages following exposure to ionizing radiation

INTRODUCTION: Progerin, the protein responsible for the Hutchinson-Gilford Progeria Syndrome (HGPS), is a partially deleted form of nuclear lamin A, and its expression has been suggested as a cause for dysfunctional nuclear membrane and premature senescence. To examine the role of nuclear envelop ar...

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Detalles Bibliográficos
Autores principales: Noda, Asao, Mishima, Shuji, Hirai, Yuko, Hamasaki, Kanya, Landes, Reid D., Mitani, Hiroshi, Haga, Kei, Kiyono, Tohru, Nakamura, Nori, Kodama, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917958/
https://www.ncbi.nlm.nih.gov/pubmed/27350809
http://dx.doi.org/10.1186/s41021-015-0018-4

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