Polycomb repressive complex 2 regulates skeletal growth by suppressing Wnt and TGF-β signalling

Polycomb repressive complex 2 (PRC2) controls maintenance and lineage determination of stem cells by suppressing genes that regulate cellular differentiation and tissue development. However, the role of PRC2 in lineage-committed somatic cells is mostly unknown. Here we show that Eed deficiency in ch...

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Detalles Bibliográficos
Autores principales: Mirzamohammadi, Fatemeh, Papaioannou, Garyfallia, Inloes, Jennifer B., Rankin, Erinn B., Xie, Huafeng, Schipani, Ernestina, Orkin, Stuart H., Kobayashi, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917962/
https://www.ncbi.nlm.nih.gov/pubmed/27329220
http://dx.doi.org/10.1038/ncomms12047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917962/
https://www.ncbi.nlm.nih.gov/pubmed/27329220
http://dx.doi.org/10.1038/ncomms12047

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