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Polycomb repressive complex 2 regulates skeletal growth by suppressing Wnt and TGF-β signalling

Polycomb repressive complex 2 (PRC2) controls maintenance and lineage determination of stem cells by suppressing genes that regulate cellular differentiation and tissue development. However, the role of PRC2 in lineage-committed somatic cells is mostly unknown. Here we show that Eed deficiency in ch...

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Detalles Bibliográficos
Autores principales:	Mirzamohammadi, Fatemeh, Papaioannou, Garyfallia, Inloes, Jennifer B., Rankin, Erinn B., Xie, Huafeng, Schipani, Ernestina, Orkin, Stuart H., Kobayashi, Tatsuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917962/ https://www.ncbi.nlm.nih.gov/pubmed/27329220 http://dx.doi.org/10.1038/ncomms12047

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