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Effect of CYP2C9, VKORC1, and CYP4F2 polymorphisms on warfarin maintenance dose in children aged less than 18 years: a protocol for systematic review and meta-analysis

BACKGROUND: Despite its shortcomings, warfarin is still the most commonly prescribed anticoagulant to prevent thromboembolism in children. In adults, numerous studies confirmed the robust relationship between warfarin maintenance doses and single nucleotide polymorphisms of cytochrome P450 2C9 (CYP2...

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Detalles Bibliográficos
Autores principales:	Takeuchi, Masanobu, Kobayashi, Tohru, Brandão, Leonardo R., Ito, Shinya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917995/ https://www.ncbi.nlm.nih.gov/pubmed/27334984 http://dx.doi.org/10.1186/s13643-016-0280-y

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