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Genomic integration of lambda EG10 transgene in gpt delta transgenic rodents
BACKGROUND: Transgenic gpt delta mouse and rat models were developed to perform gpt and Spi(−) assays for in vivo mutagenicity tests. The animals were established by integration of lambda EG10 phage DNA as a transgene into the genome. The inserted position of the transgene on chromosome was determin...
Autores principales: | Masumura, Kenichi, Sakamoto, Yasuteru, Kumita, Wakako, Honma, Masamitsu, Nishikawa, Akiyoshi, Nohmi, Takehiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918054/ https://www.ncbi.nlm.nih.gov/pubmed/27350819 http://dx.doi.org/10.1186/s41021-015-0024-6 |
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