Heterogeneity of cerebral TDP-43 pathology in sporadic amyotrophic lateral sclerosis: Evidence for clinico-pathologic subtypes

Frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS) are types of major TDP-43 (43-kDa TAR DNA-binding protein) proteinopathy. Cortical TDP-43 pathology has been analyzed in detail in cases of FTLD-TDP, but is still unclear in cases of ALS. We attempted to clarify the cor...

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Detalles Bibliográficos
Autores principales: Takeuchi, Ryoko, Tada, Mari, Shiga, Atsushi, Toyoshima, Yasuko, Konno, Takuya, Sato, Tomoe, Nozaki, Hiroaki, Kato, Taisuke, Horie, Masao, Shimizu, Hiroshi, Takebayashi, Hirohide, Onodera, Osamu, Nishizawa, Masatoyo, Kakita, Akiyoshi, Takahashi, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918136/
https://www.ncbi.nlm.nih.gov/pubmed/27338935
http://dx.doi.org/10.1186/s40478-016-0335-2

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