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Mechanisms of interstrand DNA crosslink repair and human disorders

Interstrand DNA crosslinks (ICLs) are the link between Watson-Crick strands of DNAs with the covalent bond and prevent separation of DNA strands. Since the ICL lesion affects both strands of the DNA, the ICL repair is not simple. So far, nucleotide excision repair (NER), structure-specific endonucle...

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Detalles Bibliográficos
Autores principales:	Hashimoto, Satoru, Anai, Hirofumi, Hanada, Katsuhiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918140/ https://www.ncbi.nlm.nih.gov/pubmed/27350828 http://dx.doi.org/10.1186/s41021-016-0037-9

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