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Two Linked Enteroinvasive Escherichia coli Outbreaks, Nottingham, UK, June 2014

Enteroinvasive Escherichia coli (EIEC) outbreaks are uncommon in Europe. In June 2014, two EIEC outbreaks occurred in Nottingham, UK, within 2 days; outbreak A was linked to a takeaway restaurant and outbreak B to a wedding party. We conducted 2 analytical studies: a case–control study for outbreak...

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Autores principales: Newitt, Sophie, MacGregor, Vanessa, Robbins, Vivienne, Bayliss, Laura, Chattaway, Marie Anne, Dallman, Tim, Ready, Derren, Aird, Heather, Puleston, Richard, Hawker, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918187/
https://www.ncbi.nlm.nih.gov/pubmed/27314432
http://dx.doi.org/10.3201/eid2207.152080
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author Newitt, Sophie
MacGregor, Vanessa
Robbins, Vivienne
Bayliss, Laura
Chattaway, Marie Anne
Dallman, Tim
Ready, Derren
Aird, Heather
Puleston, Richard
Hawker, Jeremy
author_facet Newitt, Sophie
MacGregor, Vanessa
Robbins, Vivienne
Bayliss, Laura
Chattaway, Marie Anne
Dallman, Tim
Ready, Derren
Aird, Heather
Puleston, Richard
Hawker, Jeremy
author_sort Newitt, Sophie
collection PubMed
description Enteroinvasive Escherichia coli (EIEC) outbreaks are uncommon in Europe. In June 2014, two EIEC outbreaks occurred in Nottingham, UK, within 2 days; outbreak A was linked to a takeaway restaurant and outbreak B to a wedding party. We conducted 2 analytical studies: a case–control study for outbreak A and a cohort study for outbreak B. We tested microbiological and environmental samples, including by using whole-genome sequencing. For both outbreaks combined, we identified 157 probable case-patients; 27 were laboratory-confirmed as EIEC O96:H19–positive. Combined epidemiologic, microbiological, and environmental findings implicated lettuce as the vehicle of infection in outbreak A, but the source of the organism remained unknown. Whole-genome sequencing identified the same organism in cases from both outbreaks, but no epidemiologic link was confirmed. These outbreaks highlight that EIEC has the capacity to cause large and severe gastrointestinal disease outbreaks and should be considered as a potential pathogen in foodborne outbreaks in Europe.
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spelling pubmed-49181872016-07-01 Two Linked Enteroinvasive Escherichia coli Outbreaks, Nottingham, UK, June 2014 Newitt, Sophie MacGregor, Vanessa Robbins, Vivienne Bayliss, Laura Chattaway, Marie Anne Dallman, Tim Ready, Derren Aird, Heather Puleston, Richard Hawker, Jeremy Emerg Infect Dis Synopsis Enteroinvasive Escherichia coli (EIEC) outbreaks are uncommon in Europe. In June 2014, two EIEC outbreaks occurred in Nottingham, UK, within 2 days; outbreak A was linked to a takeaway restaurant and outbreak B to a wedding party. We conducted 2 analytical studies: a case–control study for outbreak A and a cohort study for outbreak B. We tested microbiological and environmental samples, including by using whole-genome sequencing. For both outbreaks combined, we identified 157 probable case-patients; 27 were laboratory-confirmed as EIEC O96:H19–positive. Combined epidemiologic, microbiological, and environmental findings implicated lettuce as the vehicle of infection in outbreak A, but the source of the organism remained unknown. Whole-genome sequencing identified the same organism in cases from both outbreaks, but no epidemiologic link was confirmed. These outbreaks highlight that EIEC has the capacity to cause large and severe gastrointestinal disease outbreaks and should be considered as a potential pathogen in foodborne outbreaks in Europe. Centers for Disease Control and Prevention 2016-07 /pmc/articles/PMC4918187/ /pubmed/27314432 http://dx.doi.org/10.3201/eid2207.152080 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Synopsis
Newitt, Sophie
MacGregor, Vanessa
Robbins, Vivienne
Bayliss, Laura
Chattaway, Marie Anne
Dallman, Tim
Ready, Derren
Aird, Heather
Puleston, Richard
Hawker, Jeremy
Two Linked Enteroinvasive Escherichia coli Outbreaks, Nottingham, UK, June 2014
title Two Linked Enteroinvasive Escherichia coli Outbreaks, Nottingham, UK, June 2014
title_full Two Linked Enteroinvasive Escherichia coli Outbreaks, Nottingham, UK, June 2014
title_fullStr Two Linked Enteroinvasive Escherichia coli Outbreaks, Nottingham, UK, June 2014
title_full_unstemmed Two Linked Enteroinvasive Escherichia coli Outbreaks, Nottingham, UK, June 2014
title_short Two Linked Enteroinvasive Escherichia coli Outbreaks, Nottingham, UK, June 2014
title_sort two linked enteroinvasive escherichia coli outbreaks, nottingham, uk, june 2014
topic Synopsis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918187/
https://www.ncbi.nlm.nih.gov/pubmed/27314432
http://dx.doi.org/10.3201/eid2207.152080
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