Cargando…
Two Linked Enteroinvasive Escherichia coli Outbreaks, Nottingham, UK, June 2014
Enteroinvasive Escherichia coli (EIEC) outbreaks are uncommon in Europe. In June 2014, two EIEC outbreaks occurred in Nottingham, UK, within 2 days; outbreak A was linked to a takeaway restaurant and outbreak B to a wedding party. We conducted 2 analytical studies: a case–control study for outbreak...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Centers for Disease Control and Prevention
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918187/ https://www.ncbi.nlm.nih.gov/pubmed/27314432 http://dx.doi.org/10.3201/eid2207.152080 |
_version_ | 1782439076038705152 |
---|---|
author | Newitt, Sophie MacGregor, Vanessa Robbins, Vivienne Bayliss, Laura Chattaway, Marie Anne Dallman, Tim Ready, Derren Aird, Heather Puleston, Richard Hawker, Jeremy |
author_facet | Newitt, Sophie MacGregor, Vanessa Robbins, Vivienne Bayliss, Laura Chattaway, Marie Anne Dallman, Tim Ready, Derren Aird, Heather Puleston, Richard Hawker, Jeremy |
author_sort | Newitt, Sophie |
collection | PubMed |
description | Enteroinvasive Escherichia coli (EIEC) outbreaks are uncommon in Europe. In June 2014, two EIEC outbreaks occurred in Nottingham, UK, within 2 days; outbreak A was linked to a takeaway restaurant and outbreak B to a wedding party. We conducted 2 analytical studies: a case–control study for outbreak A and a cohort study for outbreak B. We tested microbiological and environmental samples, including by using whole-genome sequencing. For both outbreaks combined, we identified 157 probable case-patients; 27 were laboratory-confirmed as EIEC O96:H19–positive. Combined epidemiologic, microbiological, and environmental findings implicated lettuce as the vehicle of infection in outbreak A, but the source of the organism remained unknown. Whole-genome sequencing identified the same organism in cases from both outbreaks, but no epidemiologic link was confirmed. These outbreaks highlight that EIEC has the capacity to cause large and severe gastrointestinal disease outbreaks and should be considered as a potential pathogen in foodborne outbreaks in Europe. |
format | Online Article Text |
id | pubmed-4918187 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Centers for Disease Control and Prevention |
record_format | MEDLINE/PubMed |
spelling | pubmed-49181872016-07-01 Two Linked Enteroinvasive Escherichia coli Outbreaks, Nottingham, UK, June 2014 Newitt, Sophie MacGregor, Vanessa Robbins, Vivienne Bayliss, Laura Chattaway, Marie Anne Dallman, Tim Ready, Derren Aird, Heather Puleston, Richard Hawker, Jeremy Emerg Infect Dis Synopsis Enteroinvasive Escherichia coli (EIEC) outbreaks are uncommon in Europe. In June 2014, two EIEC outbreaks occurred in Nottingham, UK, within 2 days; outbreak A was linked to a takeaway restaurant and outbreak B to a wedding party. We conducted 2 analytical studies: a case–control study for outbreak A and a cohort study for outbreak B. We tested microbiological and environmental samples, including by using whole-genome sequencing. For both outbreaks combined, we identified 157 probable case-patients; 27 were laboratory-confirmed as EIEC O96:H19–positive. Combined epidemiologic, microbiological, and environmental findings implicated lettuce as the vehicle of infection in outbreak A, but the source of the organism remained unknown. Whole-genome sequencing identified the same organism in cases from both outbreaks, but no epidemiologic link was confirmed. These outbreaks highlight that EIEC has the capacity to cause large and severe gastrointestinal disease outbreaks and should be considered as a potential pathogen in foodborne outbreaks in Europe. Centers for Disease Control and Prevention 2016-07 /pmc/articles/PMC4918187/ /pubmed/27314432 http://dx.doi.org/10.3201/eid2207.152080 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
spellingShingle | Synopsis Newitt, Sophie MacGregor, Vanessa Robbins, Vivienne Bayliss, Laura Chattaway, Marie Anne Dallman, Tim Ready, Derren Aird, Heather Puleston, Richard Hawker, Jeremy Two Linked Enteroinvasive Escherichia coli Outbreaks, Nottingham, UK, June 2014 |
title | Two Linked Enteroinvasive Escherichia coli Outbreaks, Nottingham, UK, June 2014 |
title_full | Two Linked Enteroinvasive Escherichia coli Outbreaks, Nottingham, UK, June 2014 |
title_fullStr | Two Linked Enteroinvasive Escherichia coli Outbreaks, Nottingham, UK, June 2014 |
title_full_unstemmed | Two Linked Enteroinvasive Escherichia coli Outbreaks, Nottingham, UK, June 2014 |
title_short | Two Linked Enteroinvasive Escherichia coli Outbreaks, Nottingham, UK, June 2014 |
title_sort | two linked enteroinvasive escherichia coli outbreaks, nottingham, uk, june 2014 |
topic | Synopsis |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918187/ https://www.ncbi.nlm.nih.gov/pubmed/27314432 http://dx.doi.org/10.3201/eid2207.152080 |
work_keys_str_mv | AT newittsophie twolinkedenteroinvasiveescherichiacolioutbreaksnottinghamukjune2014 AT macgregorvanessa twolinkedenteroinvasiveescherichiacolioutbreaksnottinghamukjune2014 AT robbinsvivienne twolinkedenteroinvasiveescherichiacolioutbreaksnottinghamukjune2014 AT baylisslaura twolinkedenteroinvasiveescherichiacolioutbreaksnottinghamukjune2014 AT chattawaymarieanne twolinkedenteroinvasiveescherichiacolioutbreaksnottinghamukjune2014 AT dallmantim twolinkedenteroinvasiveescherichiacolioutbreaksnottinghamukjune2014 AT readyderren twolinkedenteroinvasiveescherichiacolioutbreaksnottinghamukjune2014 AT airdheather twolinkedenteroinvasiveescherichiacolioutbreaksnottinghamukjune2014 AT pulestonrichard twolinkedenteroinvasiveescherichiacolioutbreaksnottinghamukjune2014 AT hawkerjeremy twolinkedenteroinvasiveescherichiacolioutbreaksnottinghamukjune2014 |