Implications of chemokine receptors and inflammatory lipids in cancer

Inflammatory lipids receive much attention due to their important biological activities. Knowledge of the chemokine system has also reached a level that makes it interesting in clinics, which prompted clinical trials into compounds manipulating chemokines or their receptors. However, little attentio...

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Detalles Bibliográficos
Autores principales: Rolin, Johannes, Maghazachi, Azzam A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918230/
https://www.ncbi.nlm.nih.gov/pubmed/27471696
http://dx.doi.org/10.2147/ITT.S32049
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author Rolin, Johannes
Maghazachi, Azzam A
author_facet Rolin, Johannes
Maghazachi, Azzam A
author_sort Rolin, Johannes
collection PubMed
description Inflammatory lipids receive much attention due to their important biological activities. Knowledge of the chemokine system has also reached a level that makes it interesting in clinics, which prompted clinical trials into compounds manipulating chemokines or their receptors. However, little attention has been devoted to understand the relations between these two systems. Here, we will review the role of inflammatory lipids and chemokines in innate and adaptive immunity with an attempt to link the two systems and with emphasis on their importance in cancer development.
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spelling pubmed-49182302016-07-28 Implications of chemokine receptors and inflammatory lipids in cancer Rolin, Johannes Maghazachi, Azzam A Immunotargets Ther Review Inflammatory lipids receive much attention due to their important biological activities. Knowledge of the chemokine system has also reached a level that makes it interesting in clinics, which prompted clinical trials into compounds manipulating chemokines or their receptors. However, little attention has been devoted to understand the relations between these two systems. Here, we will review the role of inflammatory lipids and chemokines in innate and adaptive immunity with an attempt to link the two systems and with emphasis on their importance in cancer development. Dove Medical Press 2013-12-24 /pmc/articles/PMC4918230/ /pubmed/27471696 http://dx.doi.org/10.2147/ITT.S32049 Text en © 2014 Rolin and Maghazachi. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Rolin, Johannes
Maghazachi, Azzam A
Implications of chemokine receptors and inflammatory lipids in cancer
title Implications of chemokine receptors and inflammatory lipids in cancer
title_full Implications of chemokine receptors and inflammatory lipids in cancer
title_fullStr Implications of chemokine receptors and inflammatory lipids in cancer
title_full_unstemmed Implications of chemokine receptors and inflammatory lipids in cancer
title_short Implications of chemokine receptors and inflammatory lipids in cancer
title_sort implications of chemokine receptors and inflammatory lipids in cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918230/
https://www.ncbi.nlm.nih.gov/pubmed/27471696
http://dx.doi.org/10.2147/ITT.S32049
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AT maghazachiazzama implicationsofchemokinereceptorsandinflammatorylipidsincancer

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