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Development of antibody-based c-Met inhibitors for targeted cancer therapy

Signaling pathways mediated by receptor tyrosine kinases (RTKs) and their ligands play important roles in the development and progression of human cancers, which makes RTK-mediated signaling pathways promising therapeutic targets in the treatment of cancer. Compared with small-molecule compounds, an...

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Detalles Bibliográficos
Autores principales: Lee, Dongheon, Sung, Eun-Sil, Ahn, Jin-Hyung, An, Sungwon, Huh, Jiwon, You, Weon-Kyoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918247/
https://www.ncbi.nlm.nih.gov/pubmed/27471710
http://dx.doi.org/10.2147/ITT.S37409