Potent efficacy signals from systemically administered oncolytic herpes simplex virus (HSV1716) in hepatocellular carcinoma xenograft models

Oncolytic herpes simplex virus (HSV1716), lacking the neurovirulence factor ICP34.5, has highly selective replication competence for cancer cells and has been used in clinical studies of glioma, melanoma, head and neck squamous cell carcinoma, pediatric non-central nervous system solid tumors, and m...

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Detalles Bibliográficos
Autores principales: Braidwood, Lynne, Learmonth, Kirsty, Graham, Alex, Conner, Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918275/
https://www.ncbi.nlm.nih.gov/pubmed/27508184
http://dx.doi.org/10.2147/JHC.S71019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918275/
https://www.ncbi.nlm.nih.gov/pubmed/27508184
http://dx.doi.org/10.2147/JHC.S71019

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