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c-MET receptor tyrosine kinase as a molecular target in advanced hepatocellular carcinoma
c-MET is the membrane receptor for hepatocyte growth factor (HGF), also known as scatter factor or tumor cytotoxic factor, a mitogenic growth factor for hepatocytes. HGF is mainly produced by cells of mesenchymal origin and it mainly acts on neighboring epidermal and endothelial cells, regulating ep...
Autores principales: | Granito, Alessandro, Guidetti, Elena, Gramantieri, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918282/ https://www.ncbi.nlm.nih.gov/pubmed/27508192 http://dx.doi.org/10.2147/JHC.S77038 |
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