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Mto2 multisite phosphorylation inactivates non-spindle microtubule nucleation complexes during mitosis

Microtubule nucleation is highly regulated during the eukaryotic cell cycle, but the underlying molecular mechanisms are largely unknown. During mitosis in fission yeast Schizosaccharomyces pombe, cytoplasmic microtubule nucleation ceases simultaneously with intranuclear mitotic spindle assembly. Cy...

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Detalles Bibliográficos
Autores principales: Borek, Weronika E., Groocock, Lynda M., Samejima, Itaru, Zou, Juan, de Lima Alves, Flavia, Rappsilber, Juri, Sawin, Kenneth E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918325/
https://www.ncbi.nlm.nih.gov/pubmed/26243668
http://dx.doi.org/10.1038/ncomms8929