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The mitochondrial ubiquitin ligase MARCH5 resolves MAVS aggregates during antiviral signalling

Mitochondria serve as platforms for innate immunity. The mitochondrial antiviral signalling (MAVS) protein forms aggregates that elicit robust type-I interferon induction on viral infection, but persistent MAVS signalling leads to host immunopathology; it remains unknown how these signalling aggrega...

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Detalles Bibliográficos
Autores principales:	Yoo, Young-Suk, Park, Yong-Yea, Kim, Jae-Hoon, Cho, Hyeseon, Kim, Song-Hee, Lee, Ho-Soo, Kim, Tae-Hwan, Sun Kim, You, Lee, Youngsoo, Kim, Chul-Joong, Jung, Jae U, Lee, Jong-Soo, Cho, Hyeseong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918326/ https://www.ncbi.nlm.nih.gov/pubmed/26246171 http://dx.doi.org/10.1038/ncomms8910

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