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Lung cancer metastasis presenting as a solitary skull mass
Lung cancer has been well documented to spread to bone and the axial skeleton after metastasis to adjacent organs. Bony metastasis is not, however, the typical presenting manifestation. The differential diagnosis for a tissue mass on the skull should warrant a workup for metastatic disease. Bony met...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918473/ https://www.ncbi.nlm.nih.gov/pubmed/27340229 http://dx.doi.org/10.1093/jscr/rjw116 |
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author | Turner, Ryan C. Lucke-Wold, Brandon P. Hwang, Roy Underwood, Bill D. |
author_facet | Turner, Ryan C. Lucke-Wold, Brandon P. Hwang, Roy Underwood, Bill D. |
author_sort | Turner, Ryan C. |
collection | PubMed |
description | Lung cancer has been well documented to spread to bone and the axial skeleton after metastasis to adjacent organs. Bony metastasis is not, however, the typical presenting manifestation. The differential diagnosis for a tissue mass on the skull should warrant a workup for metastatic disease. Bony metastasis plays an important role in treatment and disease management. We report an exceptionally rare case of stage IV lung adenocarcinoma that presented with a solitary skull metastasis and a significant soft-tissue component. The lesion was treated by excision via craniotomy and subsequent medical management of the adenocarcinoma. This case illustrates a very rare presentation of lung adenocarcinoma and also represents what the authors believe to be the first report of a solitary skull mass originating from a lung primary. We also present a review of the literature surrounding bony metastasis to the skull and implications for patient care. |
format | Online Article Text |
id | pubmed-4918473 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-49184732016-06-24 Lung cancer metastasis presenting as a solitary skull mass Turner, Ryan C. Lucke-Wold, Brandon P. Hwang, Roy Underwood, Bill D. J Surg Case Rep Case Report Lung cancer has been well documented to spread to bone and the axial skeleton after metastasis to adjacent organs. Bony metastasis is not, however, the typical presenting manifestation. The differential diagnosis for a tissue mass on the skull should warrant a workup for metastatic disease. Bony metastasis plays an important role in treatment and disease management. We report an exceptionally rare case of stage IV lung adenocarcinoma that presented with a solitary skull metastasis and a significant soft-tissue component. The lesion was treated by excision via craniotomy and subsequent medical management of the adenocarcinoma. This case illustrates a very rare presentation of lung adenocarcinoma and also represents what the authors believe to be the first report of a solitary skull mass originating from a lung primary. We also present a review of the literature surrounding bony metastasis to the skull and implications for patient care. Oxford University Press 2016-06-23 /pmc/articles/PMC4918473/ /pubmed/27340229 http://dx.doi.org/10.1093/jscr/rjw116 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author 2016. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Case Report Turner, Ryan C. Lucke-Wold, Brandon P. Hwang, Roy Underwood, Bill D. Lung cancer metastasis presenting as a solitary skull mass |
title | Lung cancer metastasis presenting as a solitary skull mass |
title_full | Lung cancer metastasis presenting as a solitary skull mass |
title_fullStr | Lung cancer metastasis presenting as a solitary skull mass |
title_full_unstemmed | Lung cancer metastasis presenting as a solitary skull mass |
title_short | Lung cancer metastasis presenting as a solitary skull mass |
title_sort | lung cancer metastasis presenting as a solitary skull mass |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918473/ https://www.ncbi.nlm.nih.gov/pubmed/27340229 http://dx.doi.org/10.1093/jscr/rjw116 |
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